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Foot Blisters form when unprotected skin rubs on a rough part of the shoe, causing a skin tear, or red spot that can become an open wound, which can lead to infection. Foot blister treatment should be immediate to avoid infection and other complications.

Foot blisters form as your body's defense mechanism. A pool of bodily fluids collects under the irritated skin while a new layer of skin forms below it. This allows the skin beneath your foot blisters time to heal; however, if the outer layer of skin is punctured or torn before the lower layer heals, you are left with an open wound that is vulnerable to infection.

For people with diabetes, severe nerve damage (neuropathy) can inhibit the body's ability to feel pain, often causing minor problems such as simple foot blisters to become major complications. Though those with existing health problems are at a higher risk of developing further complications from foot blisters, everyone is at risk of infection when foot blisters form.

Foot blister treatment starts with always wearing proper fitting footwear, which can help reduce the friction and rubbing that can cause foot blisters to form. Properly fitting socks that do not wrinkle or bunch in the shoe will also help to prevent blisters.